Ct P323)P323 Pulse contour analysis for cardiac output measurement in patients after off-pump coronary artery bypass grafting: a comparison of FloTrac and PiCCOplus with intermittent thermodilutionC Hofer, D Button, A Jacomet, R Alpiger, R Tavakoli, A Zollinger Triemli City Hospital, Zurich, Switzerland Critical Care 2006, 10(Suppl 1):P323 (doi: 10.1186/cc4670) Introduction Pulse contour analysis calibrated by transpulmonary thermodilution (PiCCOplus; Pulsion Medical Systems, Munich, Germany) has shown in the past years to be a reliable alternative to the pulmonary artery catheter for cardiac output (CO) assessmentCO changes induced by body positioning.SAvailable online http://ccforum.com/supplements/10/SPCO ?ICO). A range of CO values from 2.85 to 8.60 l/min were obtained during B with significant changes of FCO, PCO and ICO between the measurement points (Table 1 and Fig. 1). The mean bias ?2SD was ?.14 ?1.82 l/min for FCO-ICO and ?.17 ?1.13 l/min for PCO-ICO. For FCO ?ICO a mean bias ?2SD of ?.8 ?36.4 was observed, whereas for PCO ?ICO the mean bias ?2SD was 0.9 ?13.2 . Conclusions These preliminary results indicate that cardiac output in patients after off-pump coronary artery bypass grafting can be reliably monitored by both tested pulse contour analysis devices (FloTrac and PiCCOplus system) during stable haemodynamic conditions. However, the FloTrac system showed a tendency to overestimate rapid decreases and increases PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/2805811 of cardiac output when compared with the PiCCOplus system. References 1. Della Rocca G, et al.: Can J Anaesth 2003; 50:707-711. 2. Felbinger TW, et al.: J Clin Anesth 2005; 17:241-248.Figure 2 (abstract P324)P324 Continuous arterial pulse cardiac output validation in hyperdynamic conditionsM Costa, P Chiarandini, G Bertossi, E Bialecka, E Venir, G Della Rocca University of Udine, Italy Critical Care 2006, 10(Suppl 1):P324 (doi: 10.1186/cc4671) Introduction Assessment of continuous cardiac output using the arterial pulse cardiac index (APCI) is nowadays available also with only standard radial artery catheterization with a transducer (Vigileo PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21804710 System, FloTracTM; Edwards Lifesciences, Irvine, CA, USA) [1,2]. It does not require calibration (thermodilution or any) but rather bases its calculations Resolvin E1 on arterial waveform characteristics in conjunction with patient demographic data. The aim of the study was to assess the level of agreement between a continuous APCI and continuous cardiac index (CCI) and intermittent cardiac index (ICI) obtained with a pulmonary artery catheter (Intellicath) in cirrhotic patients with hyperdynamic conditions. Methods Hemodynamic measurements were obtained in 14 livertransplanted patients. ICI measurements were collected after ICU admission and every 8 hours until the 48th postoperative hour. Continuous data were collected every hour after ICU admission to the 48th postoperative hour. Statistical analysis was performedFigure 1 (abstract P324)using the method described by Bland and Altman. Statistical significance was considered P < 0.05. Results Data are presented standardized by body surface area. The mean difference between APCI CI (bias ?2SD) was 0.48 ?1.40 l/min/m2 together with 95 confidence intervals of ?.92 to 1.88 l/min/m2. The mean difference between APCI CI (bias ?2SD) was 0.90 ?1.49 l/min/m2 together with 95 confidence intervals of ?.59 to 2.39 l/min/m2. Conclusions APCI obtained with the Vigileo System provided comparable measurements of cardiac output in hyperdynamic conditio.